HPE Accelerates Enterprise AI Innovation with NVIDIA Blackwell-Powered Systems and Advanced AI Models
In a significant move to empower enterprises in the age of artificial intelligence, HPE (NYSE: HPE) has unveiled major advancements to its NVIDIA AI Computing by HPE portfolio. These updates are designed to support businesses of all sizes throughout the entire AI lifecycle, from development to deployment. By deepening integration with NVIDIA AI Enterprise, HPE is bringing the latest NVIDIA AI models and blueprints to its HPE Private Cloud AI solution, enabling developers to deploy AI applications with unprecedented ease. Additionally, HPE will ship HPE ProLiant Compute servers featuring the groundbreaking NVIDIA RTX PRO 6000 Blackwell GPUs, now available in a compact 2U form factor.
HPE ProLiant Compute Servers: Powering the Future of AI
At the heart of this announcement are HPE ProLiant Compute servers, purpose-built to handle the most demanding AI workloads. These servers leverage the cutting-edge NVIDIA Blackwell architecture, delivering unparalleled performance for generative AI, agentic AI, and physical AI applications. Two key configurations of the NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs will be available:
- HPE ProLiant DL385 Gen11 Server: This air-cooled server supports up to two NVIDIA RTX PRO 6000 Blackwell GPUs in the new 2U form factor, making it ideal for data centers navigating the growing AI demands of enterprises. Its compact design ensures efficient space utilization without compromising on power or performance.
- HPE ProLiant Compute DL380a Gen12 Server: Announced earlier, this configuration supports up to eight NVIDIA RTX PRO 6000 GPUs in a 4U form factor and is set to ship in September. It offers even greater scalability and compute density, catering to organizations with intensive AI requirements.
These servers are engineered to meet the diverse needs of modern enterprises, providing the flexibility and power to innovate across industries. Whether it’s advancing robotics, enhancing visual computing, or enabling digital twins, HPE ProLiant Compute servers unlock new levels of productivity, security, and operational efficiency.
The Gen12 servers also feature multi-layered security through HPE Integrated Lights-Out (iLO) 7 Silicon Root of Trust, which includes tamper-resistant protection and quantum-resistant firmware signing. Additionally, HPE Compute Ops Management delivers centralized, cloud-native lifecycle automation, reducing IT management hours by up to 75% and minimizing downtime by 4.8 hours per server annually. Target workloads include generative and agentic AI, physical AI (such as robotics and industrial use cases), visual computing (e.g., quality control monitoring and autonomous vehicles), simulation, 3D modeling, digital twins, and enterprise applications.
HPE Private Cloud AI: A Turnkey AI Factory for Enterprises
HPE also announced the next generation of HPE Private Cloud AI, a turnkey AI factory solution co-developed with NVIDIA. Slated for release later this year, this updated solution will support NVIDIA RTX PRO 6000 GPUs alongside HPE ProLiant Compute Gen12 servers, offering seamless scalability across GPU generations, air-gapped management, and enterprise multi-tenancy.
A standout feature of the enhanced HPE Private Cloud AI is its support for the latest NVIDIA reasoning models and video blueprints, including:
- NVIDIA Nemotron Models: Designed for agentic AI, these models enable advanced reasoning capabilities that can automate complex tasks and decision-making processes.
- Cosmos Reason Vision Language Model (VLM): Tailored for physical AI and robotics, this model bridges the gap between vision and language, empowering robots and machines to interpret and interact with their environments more effectively.
- NVIDIA Blueprint for Video Search and Summarization (VSS 2.4): This blueprint allows enterprises to build AI agents capable of extracting valuable insights from vast amounts of video data, transforming raw footage into actionable intelligence.
Through continuous collaboration with NVIDIA, HPE Private Cloud AI is uniquely positioned to deliver the fastest deployment of NVIDIA NIM microservices for the latest AI models and blueprints. Accessible via HPE AI Essentials, this solution enables enterprises to harness the full potential of AI while maintaining complete control over their data. With high-performance infrastructure and robust networking capabilities, HPE Private Cloud AI addresses the surging demand for AI inferencing and accelerates AI production.
Driving Innovation Together
“HPE is committed to empowering enterprises with the tools they need to succeed in the age of AI,” said Cheri Williams, Senior Vice President and General Manager for Private Cloud and Flex Solutions at HPE. “Our collaboration with NVIDIA continues to push the boundaries of innovation, delivering solutions that unlock the value of generative, agentic, and physical AI while addressing the unique demands of enterprise workloads. With the combination of HPE ProLiant servers and expanded capabilities in HPE Private Cloud AI, we’re enabling organizations to embrace the future of AI with confidence and agility.”
Echoing this sentiment, Justin Boitano, Vice President of Enterprise AI at NVIDIA, stated, “Enterprises need flexible, efficient infrastructure to keep pace with the demands of modern AI. With NVIDIA RTX PRO 6000 Blackwell GPUs in HPE’s 2U ProLiant servers, enterprises can accelerate virtually every workload on a single, unified, enterprise-ready platform.”
Empowering the AI Revolution
As AI continues to reshape industries, the partnership between HPE and NVIDIA is paving the way for enterprises to innovate with speed and precision. By combining HPE’s robust hardware and software solutions with NVIDIA’s state-of-the-art AI technologies, businesses can tackle the challenges of today while preparing for the opportunities of tomorrow. From generative AI that fuels creativity to physical AI that powers robotics and automation, HPE is equipping organizations with the tools they need to thrive in an increasingly AI-driven world.
With these advancements, HPE is not just keeping pace with the AI revolution—it’s leading the charge, enabling enterprises to unlock new possibilities and drive transformative change across their operations.
About HPE
HPE (NYSE: HPE) is a leader in essential enterprise technology, bringing together the power of AI, cloud, and networking to help organizations achieve more. As pioneers of possibility, our innovation and expertise advance the way people live and work. We empower our customers across industries to optimize operational performance, transform data into foresight, and maximize their impact. Unlock your boldest ambitions with HPE. Discover more at www.hpe.com.
